• WEBINAR: Time for a Paradigm Change
  
• WEBINAR: Time for a Paradigm Change (YouKu - CHINA)
  

• SutterPatch Informational Video
• SutterPatch Walk-Through: #1 Introduction
• SutterPatch Walk-Through: #2 Amplifier Control
• SutterPatch Walk-Through: #3 Routines
• SutterPatch Walk-Through: #4 Data Navigator and Metadata
• SutterPatch Walk-Through: #5 Application Modules
• WEBINAR: Dynamic Clamp and Cross-Experiment Analysis
• WEBINAR: Dynamic Clamp and Cross-Experiment Analysis (Youku)
• WEBINAR: Puller Maintenance & Imaging with Patch Clamp
• WEBINAR: Puller Maintenance & Imaging with Patch Clamp (Youku)

• Dolzer J (2021): Patch Clamp Technology in the Twenty-First Century. In: Dallas M., Bell D. (eds): Patch Clamp Electrophysiology. Methods in Molecular Biology 2188:21-49. doi:10.1007/978-1-0716-0818-0_2
• Spratt PWE, Alexander RPD, Ben-Shalom R, Sahagun A, Kyoung H, Keeshen CM, Sanders SJ, Bender KJ (2021): Paradoxical hyperexcitability from NaV1.2 sodium channel loss in neocortical pyramidal cells. Cell Reports 36(5):109483. doi:10.1016/j.celrep.2021.109483
• Xia P, Laskur MAR, Wang, C (2023) Wafer-Scale Fabrication of Uniform, Micrometer-Sized, Triangular Membranes on Sapphire for High-Speed Protein Sensing in a Nanopore. ACS Appl Mater Interfaces 15(2):2656–2664. doi:10.1021/acsami.2c18983
• Brown SP, Lawson RJ, Moreno JD, Ransdell RL (2024): A Reinterpretation of the Relationship between Persistent and Resurgent Sodium Currents. J Neurosci 44 (29):e2396232024. doi:10.1523/JNEUROSCI.2396-23.2024

• Liddiard GT, Suryavanshi PS, Glykys J (2024): Enhancing GABAergic Tonic Inhibition Reduces Seizure-Like Activity in the Neonatal Mouse Hippocampus and Neocortex. J Neurosci 44(7):e1342232023. doi:10.1523/JNEUROSCI.1342-23.2023

• Aimino MA, Coker CR, Silberman Y (2018) Acute ethanol modulation of neurocircuit function in the nucleus of the tractus solitarius. Brain Res Bull 138:5-11. doi:10.1016/j.brainresbull.2017.07.019

• Anderson EM, Gomez D, Caccamise A, McPhail D, Hearing M. (2019) Chronic unpredictable stress promotes cell-specific plasticity in prefrontal cortex D1 and D2 pyramidal neurons. Neurobiol Stress 10:100152. doi:10.1016/j.ynstr.2019.100152
• Avelar AJ, Akers AT, Baumgard ZJ, Cooper SY, Casinelli GP, Henderson BJ (2019) Why flavored vape products may be attractive: Green apple tobacco flavor elicits reward-related behavior, upregulates nAChRs on VTA dopamine neurons, and alters midbrain dopamine and GABA neuron function. J Neuropharm 158:107729. doi:10.1016/j.neuropharm.2019.107729
• Doncheck EM, Anderson EM, Konrath CD, Liddiard GT, DeBaker MC, Urbanik LA, Hearing MC, Mantsch JR (2021): Estradiol Regulation of the Prelimbic Cortex and the Reinstatement of Cocaine Seeking in Female Rats. J Neurosci 41(24):5303-5314. doi:10.1523/JNEUROSCI.3086-20.2021
• Driscoll JR, Wallace TL, Mansourian KA, Martin WJ, Margolis EB (2020): Differential Modulation of Ventral Tegmental Area Circuits by the Nociceptin/Orphanin FQ System. eNeuro 7(5):ENEURO.0376-19.2020. doi:10.1523/ENEURO.0376-19.2020
• Feng T, Alicea C, Pham V, Kirk A, Pieraut S (2021): Experience-Dependent Inhibitory Plasticity Is Mediated by CCK+ Basket Cells in the Developing Dentate Gyrus. J Neurosci 41(21):4607-4619. doi:10.1523/JNEUROSCI.1207-20.2021
• Hu H, Wang X, Li C, Li Y, Hao J, Zhou Y,Yang X, Chen P, Shen X, Zhang S (2021): Loss of Dysbindin Implicates Synaptic Vesicle Replenishment Dysregulation as a Potential Pathogenic Mechanism in Schizophrenia. Neurosci 452:138-152. doi:10.1016/
• Hurley MM, Anderson EM Chen C, Maunze B, Hess EM, Block ME, Patel N, Cooper Z, McCoy R, Dabra T, Conley W, Reilly MJ, Hearing M, Choi S (2019) Acute Blockade of PACAP-Dependent Activity in the Ventromedial Nucleus of the Hypothalamus Disrupts Leptin-Induced Behavioral and Molecular Changes in Rats. Neuroendocrinol 110:271-281. doi:10.1159/000501337
• Hutto RA, Bisbach CM, Abbas F, Brock DC, Cleghorn WM, Parker ED, Bauer BH, Ge W, Vinberg F, Hurley JB, Brockerhoff SE (2019) Increasing Ca2+ in photoreceptor mitochondria alters metabolites, accelerates photoresponse recovery, and reveals adaptations to mitochondrial stress. Cell Death Differ 27:1067-1085. doi:10.1038/s41418-019-0398-2
• Madayag AC, Gomez D, Anderson EM, Ingebretson AE, Thomas MJ, Hearing MC (2019). Cell-type and region-specific nucleus accumbens AMPAR plasticity associated with morphine reward, reinstatement, and spontaneous withdrawal. Brain Struct Funct 224:2311. doi:10.1007/s00429-019-01903-y
• McDevitt DS, Jonik B, Graziane NM (2019) Morphine differentially alters the synaptic and intrinsic properties of D1R- and D2R-expressing medium spiny neurons in the nucleus accumbens. Front Synaptic Neurosci 11:35. doi:10.3389/fnsyn.2019.00035
• McGovern DJ, Polter AM, Root DH (2021): Neurochemical Signaling of Reward and Aversion to Ventral Tegmental Area Glutamate Neurons. J Neurosci 41(25):5471-5486. doi:10.1523/JNEUROSCI.1419-20.2021
• Nissenkorn A, Almog Y, Adler I, Safrin M, Brusel M, Marom M, Bercovich S, Yakubovich D, Tzadok M, Ben-Zeev B, Rubinstein M (2019) In vivo, in vitro and in silico correlations of four de novo SCN1A missense mutations. PLoS ONE 14(2):e0211901. doi:10.1371/journal.pone.0211901
• Oda K, Vierock J, Oishi S, Rodriguez-Rozada S, Taniguchi R, Yamashita K, Wiegert JS, Nishizawa T, Hegemann P, Nureki O (2018) Crystal structure of the red light-activated channelrhodopsin Chrimson. Nat Commun 9(1):3949. doi:10.1038/s41467-018-06421-9
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• Qneibi M, Jaradat N, Hawash M, Olac A, Emwas N (2020): Ortho versus Meta Chlorophenyl-2,3-Benzodiazepine Analogues: Synthesis, Molecular Modeling, and Biological Activity as AMPAR Antagonists. ACS Omega 5(7):3588. doi:10.1021/acsomega.9b04000
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dPatch

• Quick Start Guide
• Operation Manual

IPA

• Quick Start Guide
• Operation Manual

Dendrite

• Quick Start Guide
• Operation Manual

Telly Galiatsatos

Contact Info:

sutterpatch@sutter.com

SutterPatch Software comes as part of the IPA®, Double IPA®, dPatch®, and Dendrite™ Amplifier and Acquisition Systems and includes a multi-user license (3-seat) of Igor Pro 9® by WaveMetrics, Inc. The full installers available on this page are for Igor Pro 9.

SutterPatch v3.0 (build 370); December 15^th, 2023 - Release Notes

Windows Installers (Windows 10 or later, 64-bit)

• Full Installer for Windows, Igor Pro 9 > Download
• SutterPatch Updater for Windows, Igor Pro 9 > Download

Macintosh Installers (OS X 10.14 or newer)

• Full Installer for OSX, Igor Pro 9 > Download

Notes:

We do not recommended using the SutterPatch Updater to install SutterPatch Software on top of an existing standalone installation of Igor Pro. If you already have Igor Pro 9 on your computer, please use one of the following methods to install SutterPatch Software:
• Use the Full Installer to update the existing Igor Pro and install SutterPatch.
• Uninstall Igor Pro and install SutterPatch using the Full Installer. Remember to backup your Igor user files before uninstalling!
• Create a second installation of Igor Pro using the Full Installer. This should only be done in special cases and is not advised.

SutterPatch 3.0 is ONLY compatible with Igor Pro 9, 64-bit. As of May 2023, a three seat multi-user license of Igor Pro 9 has been bundled with all our amplifier systems. For users that need to upgrade, the following options are available directly from WaveMetrics:
• Part 17-525, Igor Pro 9 Upgrade from Igor 8, single-user, $200
• Part 17-560, Igor Pro 9 Multi-user OEM License 2-seat Addition
• Part 17-565, Igor Pro 8-to-9 Multi-user OEM License Upgrade & 2-seat Addition

Igor Pro 9 and SutterPatch v.2.2 Software may be installed in addition to existing installations of older versions of Igor Pro and/or SutterPatch Software. All settings and parameters are independent between versions. Please see the System Requirements tab for the full list of hardware and software requirements.

Software Trial
If you are planning to evaluate SutterPatch, you can activate a trial license of Igor Pro 9. After 30 days, a number of features, such as saving, printing and copying to the clipboard will be disabled.

dPatch Firmware version 101; November 3^rd, 2023

dPatch Firmware Upgrade Instructions
SutterPatch 3.0 includes dPatch firmware version 101; November 3rd, 2023. When SutterPatch is started it will automatically check the firmware version as part of the dPatch amplifier initialization sequence. If a newer version is available a prompt will be displayed advising to update the firmware, which is highly recommend.  The prompt will guide you through the update process, or it can be initiated via the menu SutterPatch > Hardware Control > dPatch Maintenance – Update Firmware.
The firmware binary file can be found in:
Windows:    Program Files/SutterPatch3/Tools Folder

Macintosh:    Applications/SutterPatch3/Tools Folder

Or it can be downloaded: Download dPatch Firmware Version 101