MP-225 Based Multi-Micromanipulator Systems

The MPC-325 System consists of the MPC-200 controller and one to four MP-225 micromanipulators.

MPC-200 Controller and ROE

Neurobiological experiments are becoming more complex. Many require multiple manipulators with control units that quickly become space and/or cost prohibitive. The MPC-200 is the solution you have been asking for. A single controller capable of running 2 manipulators! Sutter Instrument has taken the simplicity of the MP-225 controller and expanded it to run two manipulators from a single controller/ROE. The MPC-200 works with one or two of our world-renowned mechanicals, the MP-285 (MPC-385), the MP-225 (MPC-325) or the narrow format MP-865 (MPC-365).

If two manipulators aren't enough, a second controller can be daisy chained to allow the single ROE-200 to move up to four manipulators. Thus the system can be easily expanded to control highly sophisticated experiments.

The Sutter MPC-200 is electrically quiet. Unlike the competition, our multi-unit controller employs linear output circuitry. Sutter adds additional manipulators to the same controller without requiring potentially noisy chopper drives.

In all our manipulators, the 4th axis can be set up and changed without the need to connect an external computer to download and configure software. A separate configuration is allowed for each output on this manipulator controller. If desired, each manipulator can approach the prep at a different angle from the horizontal. The 4th axis can be configured between the X and Z axes or the Y and Z axes (useful when manipulator is rotated 90 degrees relative to the preparation).

Faster automated pipette exchange. The MPC-200 has faster “Home” and “Work Position” moves for quicker pipette exchange. Automation is set up and run via the same interface used in the MP-225 controller; however, the speeds of the automated movement are much faster.

Accelerated manual mode. For users who prefer manual pipette exchange we have added “Accelerated Mode” to the ROE. Using Accelerated Mode, the user can make quick manual moves in and out of a setup. Accelerated Mode amplifies the speed attainable in a manual move by smoothly accelerating to the maximum speed during sustained, fast turns of the ROE. Accelerated movement ends as soon as the user stops turning the knob. This mode can be fully disabled for those who feel the need for direct control of the pipette.

MP-225 Micromanipulator

The MP-225 manipulator represents an economical alternative to the MP-285 and MPC-365. In 2002, production and design changes allowed us to produce this motorized manipulator as a more affordable alternative to the industry standard MP-285. The mechanical design utilizes a miniature stepper motor and integral anti-backlash gear head. Pre-loaded ball bearing slides provide smooth movement throughout the 25 mm of travel. The methodology for mounting pipette holders and headstages used with the MP-285 has been maintained in the MP-225 to allow for cross compatibility.

Additional component pieces can be added at any time, allowing the user to develop a system tailored to his or her particular needs. The controller is self-detecting so there is no need for manual configuration of the components.

  • Quietest electronics in the industry optimized for single channel recording
  • Single controller and ROE will run two stepper motor drive manipulators
  • Self-detecting, daisy-chain capability allows control of four manipulators from one ROE-200
  • User-friendly interface: single button access to all major functions
  • Easily configurable virtual 4th axis set without external computer
  • Accelerated Mode for fast, manual manipulator movement
  • Easy toggle selection of Mode (speed/resolution, pulsed diagonal, Accelerated Mode)
  • Display indicates X, Y, Z coordinates, Mode, active manipulator
  • Robotic Home and Work Position moves for easy automated pipette exchange
  • Faster robotic moves than previous versions
  • Definable 4th axis for coaxial pipette movement, angle selected by DIP switches
  • Simple USB interface
  • Toggle switch selects which manipulator is connected to input device
  • LED and display indicate active manipulator
  • Ultra-low drift, ultra-smooth movement
  • Low-drift mechanical stability


Resolution and Full Travel
Minimal microstep size is 62.5 nanometers per microstep
Display has single micron resolution
Full travel is 25 mm in each axis

Maximum Speed
MP-225 mechanical
3 mm/sec

Long Term Stability
< 1.0 micron in 2 hours

MPC-200 Controller
15.75 in x 10.75 in x 3.5 in | 40 cm x 27.3 cm x 9 cm
10 in x 6 in x 4 in | 25 cm x 15 cm x 23 cm

MPC-200 Controller
6.5 lbs | 3 kg
3.5 lbs | 1.6 kg

115/230 Volts
50/60 Hertz power line

RoHS Compliant

MPC-200 CE Certificate

MPC-325 CE Certificate

US Prices > MPC-200/MPC-385/MPC-325
International prices vary by country. Please contact your local distributor or Sutter Instrument for a quotation. Prices subject to change without notice.

Catalog Number Description Price
MPC-325* One MP-225 manipulator mechanical, one MPC-200 controller, one ROE-200, mounting adapter plate, rod holder, hinged headstage mount, 4" dovetail extension, manipulator and ROE connecting cables, power cord and manual $ 10,227
MPC-325-2* MPC-325 with (2) MP-225 mechanicals $ 15,396
MPC-325-3* MPC-325 with (3) MP-225 mechanicals and (2) MPC-200 controllers $ 25,621
MPC-325-4* MPC-325 with (4) MP-225 mechanicals and (2) MPC-200 controllers $ 30,791
* Indicate right- or left-handed set-up when ordering


Catalog Number Description Price
MPC-200-ROE Consists of the MPC-200 controller and ROE-200. This “system” is made available at a special price for those who wish to upgrade previously purchased Sutter manipulators with the newer controller system or to use the MPC-200-ROE to control other devices. Includes cable to connect ROE to controller, power cord and manual $ 5,060
MPC-200 Controller box alone. Purchase this if you intend to daisy-chain two controllers to one ROE-200. In this configuration, up to four manipulators can be controlled by a single ROE-200. NOTE: This is not a stand-alone device. In order to function, the MPC-200 must be connected to a second MPC-200 with ROE-200 attached or be connected to its own ROE-200. Includes daisy chain cable, power cord and manual $ 3,754
ROE-200 This is the ROE alone. Provides user input to one or more MPC-200 controllers. This component is intended for users who have an existing four-manipulator MPC-200 system with a single ROE-200 and wish to split it into two independent two-manipulator systems. Includes cable to connect ROE to controller $ 2,041
MP-285/M* MP-285 manipulator mechanical alone - Includes mounting adapter plate, rod holder, 4" dovetail extension, hinged headstage mount and cable to connect manipulator to controller. $ 7,378
MP-225/M* MP-225 manipulator mechanical alone - Includes mounting adapter plate, rod holder, 4" dovetail extension, hinged headstage mount and cable to connect manipulator to controller. $ 6,374
* Indicate right- or left-handed set-up when ordering


Catalog Number Description Price
285204 4 in dovetail extension $ 82
285210 1 Mounting adapter plate $ 86
225RBI Rotating base $ 930
285300 Right angle adapter $ 129
285305 Z-axis vertical extension $ 129
285310 Z-axis horizontal extension $ 129
BR-AW Rod holding clamp for XenoWorks® injectors (for rod OD 2-4 mm) $ 125
BR-AW-L Long Rod holding clamp for XenoWorks® injectors (for rod OD 2-4 mm) $ 147
MP-CLIP2 Rod holder (for rod OD 1 mm to 4 mm) $ 125
MP-ROD Rod holder (for rod OD 6.25 mm or larger) $ 125
285HEA Hinged headstage mount $ 494
M100106 Flat side panel for controller (each) $ 50
MP-RISER-0.53 1/2 inch riser $ 165
MP-RISER-1.03 1 inch riser $ 226
EHOLDER Micropipette holder - 1.0-1.5 mm glass $ 147

1 For use with MT and MD series stands and platforms, or any surface with 1 inch or 25 mm centered holes
2 Suitable for multielectrode probes
3 For MP-225 mechanical only - risers can be combined to achieve desired height

For detailed information on mounting our micromanipulators, refer to the Mounting Systems section or phone for assistance.

MT-1078 / MT-2078
MT-1000 / MT-2000
MD Series