The XenoWorks® Micromanipulator has been designed around our hugely successful MP-285 electrophysiology micromanipulator mechanical, with the addition of a smooth-moving, adjustable, inverted joystick. Because the three-axis mechanical is based on an electrophysiology design, the XenoWorks Micromanipulator is extremely stable and resistant to ambient vibration. This stability makes the manipulator an ideal platform for intracytoplasmic sperm injection (ICSI), particularly when used in combination with the PrimeTech PMM6, PMM4G or PMM150FU Piezo Impact Drive Systems. It is also ideal for animal and cellular research that requires microinjection, aspiration, and transfer into eggs, cells or tissue, including CRISPR, nuclear transfer and biopsy.

The redesigned XenoWorks joystick offers an unprecedented level of user comfort during operation. The controller circuitry is fully integrated into the joystick, fanless and completely silent. The use of an inverted, height- and tension-adjustable joystick, in conjunction with the functionally shaped base, allows the operator to rest their hands and forearms on the bench surface, providing ease of use and added ergonomics. The function keys and declutch band can be located and activated by touch, removing the need to look away from the microscope. Additional time-saving features are the user-defined Home position, two user-defined Work positions, and the Setup function, which centers the manipulator in all three axes.

The newly introduced Diagonal mode enables motion in the axis of the pipette. Combining diagonal mode with the new Pulse motion facilitates penetrating specimens with a resilient membrane, cuticle or chorion. To eliminate guesswork, the status of all functions and motions is shown in the convenient LED display.

Lock functions for both the X and Y axes allow restricting movement to only two dimensions for maximum control during injections. The Z-Floor memory position is used to prevent the pipette from colliding with the bottom of the dish, while the equivalent function for the X axis is useful for repetitive injections into a parallel row of eggs.

The XenoWorks joystick is designed to allow the user to immediately develop an intuitive feel that makes it easy to precisely control the position. Movement of the joystick is directly converted to a proportional movement of the manipulator. Speed control, center of travel, and programmable positions are right at your fingertips. One unique feature of the joystick is the declutch band that allows for easy repositioning of the joystick without moving the pipette. The declutch band is also used as a modifier key, which gives individual buttons additional functions. Combining this advanced joystick with the proven Sutter manipulator technology creates an ideal system for efficient microinjection.

  • Joystick and controller integrated into a single unit eliminates the need for a separate component
  • Inverted joystick with adjustable height and tension for optimal ergonomics
  • Exceptionally smooth and responsive micropipette movement
  • Diagonal mode operation for axial pipette movements
  • One-click, axial ‘Pulse’ operation helps penetrate tough membranes
  • User-defined “Home” position and “Work” positions for fast micropipette exchange
  • User-defined limits for travel along Z-axis and X-axis
  • Locks for X- and Y-axes permit pure movements along Y- and X-axes
  • 25 mm of travel in all three axes
  • Touch declutch mechanism
  • 8 speeds from coarse to ultra-fine
  • USB computer interface for external programmable control


25 mm on all three axes

Maximum Resolution
125 nm/microstep

Maximum Speed
3.25 mm/sec


X & Y Axis
(per swing of joystick)
Z axis
(per rotation of knob)
C 15.9 mm 3.2 mm
1 4.1 mm 800 µm
2 1.1 mm 400 µm
3 500 µm 200 µm
4 250 µm 100 µm
5 125 µm 50 µm
6 100 µm 30 µm
7 50 µm 10 µm

Joystick Controller Features
  • Inverted joystick
  • Adjustable height and tension
  • Independent control of X, Y, and Z axes
  • Setup function
  • Touch declutch
  • Z-floor axis limit
  • X-axis limit
  • Y-axis lock
  • X-axis lock
  • Diagonal Mode
  • 8 Speed settings
  • 1 user-defined Home position
  • 1 user-defined Work position
  • 2 user-defined axis limits: Z-Floor & X-Limit
  • Pulse Mode, 3 μm diagonal advance

4.4 x 7.3 x 5.7 in | 11.2 x 18.5 x 14.5 cm

Joystick Controller
11.4 x 9.3 x 9.6 in | 28.9 x 23.5 x 24.4 cm

120/240 Volts
50/60 Hertz power line

US Prices > XenoWorks® Micromanipulator
International prices vary by country. Contact a distributor or Sutter Instrument for a quotation. Prices subject to change without notice.

Catalog Number Description Price
XWML XenoWorks Micromanipulator (Left) includes: 3 axis motor drive (left-hand configuration), motor drive base plate, joystick controller, connecting cables, and manual $ 16,450
XWMR XenoWorks Micromanipulator (Right) includes: 3 axis motor drive (right-hand configuration), motor drive base plate, joystick controller, connecting cables, and manual $ 16,450
XW-JOY XenoWorks Joystick Controller, power supply, and manual; for use with existing XenoWorks or MPC-285/M mechanicals $ 7,230

US Prices > XenoWorks Microscope Adapters

Catalog Number Description Price
BR-L20 Leica DMIRB/E/IRE2 Adapter $ 1,355
BR-L30 Leica DMIL Adapter $ 1,355
BR-L40-2 Leica DMI 4/5/6000/8 Adapter (double-sided) $ 2,651
BR-N10 Nikon TMD Adapter $ 1,355
BR-N25 Nikon TE200/300 Adapter $ 1,355
BR-N27 Nikon TE2000 Adapter $ 1,355
BR-N29 Nikon Ti Adapter $ 2,120
BR-N29-M Nikon Ti Adapter for scopes w/ motorized stage $ 2,120
BR-Y50 Olympus IX50/70 Adapter $ 1,355
BR-Y51 Olympus IX51/71/81 Adapter $ 1,355
BR-Y51-FL Olympus IX51/71/81 Adapter w/ ZDC autofocus (left) $ 1,355
BR-Y51-FR Olympus IX51/71/81 Adapter w/ ZDC autofocus (right) $ 1,355
BR-Y73 Olympus IX53/73/83 Adapter $ 2,027
BR-Y73-2 Olympus IX53/73/83 Adapter (double-sided) $ 2,651
BR-Z30 Zeiss Axiovert 100/135 Adapter $ 1,355
BR-Z40 Zeiss Axiovert 200 / Axio Observer Adapter $ 1,095
BR-Z50 Zeiss Axiovert A1 Adapter $ 1,813
BR-CUST Custom microscope adapter, e.g., for aftermarket microscope stage or accessories $ CALL

US Prices > XenoWorks Accessories

Catalog Number Description Price
BR-AW Rod holding clamp (for rod OD 2-4 mm), 2 in (5.0 cm) long $ 125
BR-AW-L Rod holding clamp (for rod OD 2-4 mm), 3 in (7.5 cm) long $ 147
MT-81-DOV81 MT-81 gantry stand with 8 inch (20 cm) dovetail;
Clearance 1.75 to 6.5 in (4.5 to 16.5 cm)
Mounting height 2.5 to 7.25 in (6.4 to 18.4 cm)
$ 755
MAG-SB-MT Magnetic feet for small baseplate (set of 4) $ 86
X050055 Magnetic plate for gantry equipped with magnetic feet $ 345
BRM-ADPTR-PLT2 XenoWorks adapter mounting plate with dovetail fitting;
5.75 x 6 x 0.3 in (14.5 x 15.5 x 0.8 cm)
$ 531
BR-HEA-CV3 Swing gate conversion for MP-285 / MP-225 $ 509

1 Useful with stereo or dissection scopes
2 Included with XenoWorks Microscope Adapters
3 Factory installation required. No charge when ordered with manipulator

XenoWorks Digital Microinjector
PrimeTech Piezo Impact Drive
P-97 Micropipette Puller
P-1000 Micropipette Puller
BV-10 Micropipette Beveler

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