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XenoWorks
Micromanipulator
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P E C I F I C A T I O N S > |
| MICROMANIPULATOR
Travel
25mm on all three axes
Maximum Resolution
62.5nm/microstep
Maximum
Speed
5.5mm/sec
Range
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X
& Y Axis
1 joystick swing |
Z
axis
1 rotation |
| C |
12,700
µm |
3,200
µm |
| 1 |
3,300µm |
800
µm |
| 2 |
880
µm |
400
µm |
| 3 |
400
µm |
200
µm |
| 4 |
200
µm |
100
µm |
| 5 |
100µm |
50
µm |
Joystick
• Inverted joystick with integral declutch
• Height and resistance adjustable
• Independent axis-polarity inversion
• Independent axis-polarity switches
• 6 speed settings
• 'Setup' function
• 1 user-defined set point ('Work')
• 1 user-defined axis limit ('Z-floor')
• 2 preset points ('Home' and 'Setup')
• Y-axis lockout
Maxmimum Motor Speed / Travel Range
5.5mm/s / 25mm
Dimensions
Motor drive:
112mm x 185mm x 145mm
Joystick:
265mm x 240mm x 226mm
Control:
407mm x 280mm x 101mm
Electrical
115/230 Volts AC
50/60 Hertz powerline
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The
XenoWorks Micromanipulator has been designed around our
hugely-successful MP-285 electrophysiology micromanipulator,
with the addition of a smooth-moving adjustable inverted joystick. Because
the motor drive is based on an electrophysiology design, the XenoWorks
Micromanipulator is extremely stable and resistant to
ambient vibration. This stability also makes this manipulator an ideal
platform for use in conjunction with the PrimeTech PMM-150FU
piezo impact drive for applications such as mouse nuclear transfer and
intracytoplasmic sperm injection.
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E A T U R E S >
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XENOWORKS
MICROMANIPULATOR
Height and tension adjustable inverted joystick for optimal ergonomics
Exceptionally smooth and responsive micropipette movement
"Home" position for fast micropipette exchange
User definable memory positions, including Work and Z-axis lower limit
Y-axis lock-out for pure X-axis travel
25mm of travel in all three axes
Touch declutch mechanism
6 speeds from coarse to ultra-fine
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The joystick offers an unprecedented level of user comfort
during operation. The use of an inverted joystick in conjunction with
an almost zero-profile base allows the operator to rest their hands and
forearms on the bench surface, reducing the risk of repetitive strain
injuries. The function keys can be located and activated by touch, obviating
the need to look away from the microscope, saving time. Another time saving
feature is the "Setup" function. Activating the setup function
places the micromanipulator in the optimum position prior to beginning
work (halfway on the Y-axis, three-quarters down on the Z-axis and three-quarters
inwards on the X-axis). Once the manipulator is in the default setup position,
the micropipette tip will already be projecting into the microscope's
optical path, reducing the time taken to find the pipette tip through the
microscope. The setup function also ensures an adequate travel range in all
axes of motion prior to starting work.
The micromanipulator uses a pre-programmed "Home" position for fast
micropipette exchange, and the ability to determine a "Work" position
so the pipette can be repositioned with the press of a button. A Y-axis lockout
function allows X-only axial movement for maximum control during injections, and
a Z-limit memory position is used to prevent the pipette from colliding with the
bottom of the dish.
The XenoWorks joystick is designed to allow the user to immediately develop
an intuitive feel that makes it easy to precisely control position. Movement of the
joystick is directly converted to a proportional movement of the manipulator. Speed
control, center of travel, and programmable positions are right at your fingertips.
One unique feature of the joystick is the declutch mechanism that allows for rapid
repositioning of the joystick without moving the pipette. Combining this advanced
joystick with the proven Sutter MP-285 manipulator technology creates an ideal
system for intensive microinjection.
The configuration of any microinjection system will depend
upon the application for which it is used. Some common applications and
system configurations are:
- Zygote pronuclear DNA microinjection
- Embryonic stem cell transfer into blastocyst
- Intracytoplasmic Sperm Injection (ICSI)
- Piezo-assisted ICSI
- Microinjection of cultured, adherent cells
- Somatic cell nuclear transfer

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