The MP-78 Large Moving Stage is available for patch slice or in vivo experiments where the microscope body cannot be moved to view different fields of view. This is most common in two-photon experiments where the excitation beam path must enter a fixed microscope. In order to visit wide-spaced fields of view, and potentially position pipettes at wide-spaced locations, the preparation and any associated manipulators must move together on a large stage.

The MP-78 was introduced at the 2007 Imaging Structure and Function in the Nervous System at Cold Spring Harbor Labs. The stage was very well received. The MP-78 is also appropriate for use with inverted microscopes or other scopes that are larger and not easily translated.

The cast aluminum top plate used in the MP-78 has an attractive shape with an extensive 1/4-20 threaded hole pattern on 1-inch centers. This hole pattern is appropriate for mounting Sutter MP-285 or MP-225 manipulator mechanicals using the mounting adapter plates that come with these devices. Optional rotating bases (285RBI) are also compatible and add flexibility. Finally, the new, MP-265/M mechanical can be mounted on its narrow linear slide.

The large-stage platforms provide solid, stable support and ample space to attach manipulators and other instruments as needed. The rigid aluminum top plate sits firmly on two of our well-known MT-75 gantry-style stands. These stands provide height adjustment and sturdy attachment to the user’s vibration table. Multiple degrees of freedom accommodate a variety of microscope and instrument arrangements.

In the center of the MP-78 top plate is a 4X6 inch milled pocket that will accommodate a variety of aluminum stage inserts, designed to secure various commercial tissue chambers or slide holders. Custom aluminum inserts can also be provided. An available magnetic stainless steel insert carries commercial chambers or can be provided with a simple large, through hole for mounting a custom chamber. The magnetic insert allows small magnetic devices (perfusion lines, ground electrodes, small manipulators) to be mounted easily near the dish.